Secondary metabolites regulation

Ruiz B, Chavez A, Forero A, Garcia-Huante Y, Romero A, Sanchez M, Rocha D, Sanchez B, Rodriguez-Sanoja R, Langley E, Sanchez S. (2010) Secondary metabolites Regulation by the carbon source. CritRev Microbiol 36 146-167. 

These dynamic strategies also play important roles in the chemical defense of benthic organisms. Only in recent years have marine scientists started to apply methods that allow these defensive strategies to be monitored. This opens the field for the identification of signals that play a role in species-species interactions in the marine environment and for the elucidation of hormones responsible for regulating the production of secondary metabolites. 

Horseradish peroxidase (HRP) is an extracellular plant enzyme that acts in regulation of cell growth and differentiation, polymerization of cell wall components, and the oxidation of secondary metabolites essential for important pathogenic defense reactions. Because of these essential functions, and also because of its stability and ready availability, HRP has attracted considerable attention.13 It has been involved in a number of applications, such as diagnostic assays,14 biosensors,15 bioremediation,16 polymer synthesis,17 and other biotechnological processes.18 More applications in which HRP catalysis is translated into an electrochemical signal are likely to be developed in the near future. 

Similar to the CNBM, the GDBM has been regarded as a supply-side model, as it emphasizes that the levels of defenses are indirectly determined by the supply of secondary metabolites, rather than actively regulated in order to fulfill defensive demands. The GDBM is based on the premise that there is a physiological trade-off... 

Foley WJ, Moore BD (2005) Plant secondary metabolites and vertebrate herbivores - from physiological regulation to ecosystem function. Curr Opin Plant Biol 8 430 135 Freeland WJ (1991) Plant secondary metabolites biochemical coevolution with herbivores. In Palo RT, Robbins CT (eds) Plant defenses against mammalian herbivory. CRC, Boca Raton, FL, pp 61-81... 

Piepersberg, W. Diaz-Guardamino, P. M. Zhang, C. S. Stratmann, A. Wehmeier, U. F. Recent advances in biosynthesis and regulation of aminoglycosides. In Microbial Secondary Metabolites, Fierro, F. Martin, J. F. Eds. Kerala, India Research Signpost, 2002 pp. 1-26. 

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