Secondary containers transporting agents

Peptides and proteins provide significant promise as they can be prepared by a facile synthetic process (solid-phase synthesis in the case of peptides) or isolated in quantity (in the case of protein) and are amenable to derivatization or mutation. In the case of protein exploitation, the secondary, tertiary, and quaternary structures are also important for orientation and association. The viral capsid, and in particular its regular icosahedral surface, has been recently exploited as a molecular container and a biotemplate for nanomaterials (Figure 6b).The ability of viruses to enter all types of cells including human implies that they are ideally suited as noninfectious transport agents for wholly synthetic entities, not just nucleic acids. 

During the operation of the RRS to destroy CAIS at DCD, some public interest groups raised concerns about the Army s plans to transport and destroy secondary waste streams from the RRS, which may contain trace amounts of agent as well as high concentrations of chloroform, in a commercial incinerator.Similar concerns may be raised at other sites to which the RRS is deployed. 

In some cases, secondary waste treatment could be deployed to the site where primary treatment is conducted. Given potential public opposition to sending secondary wastes off-site, this may be the preferred option. However, as indicated previously, secondary wastes from mobile treatment technologies are not expected to contain amounts of chemical agent or other chemicals that would render the materiel acutely hazardous. The committee believes that this materiel may safely be transported off-site or off-installation to a TSDF for treatment. In this case, the treatment would be conducted under the permit for an off-site TSDF. If the permit for the off-site TSDF is not written broadly enough to allow treatment of these secondary wastes, it may need to be modified. In this case, provisions for permit modification should be considered well ahead of initial treatment of the NSCWM. See Appendix F for additional information on RAP alternatives. 

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