Second step NMP

Commercial end functional polymers have been converted to alkoxyamines and used to prepare PEO-Woci-PS. The hydroxyl group of alkoxyamine 284 was used to initiate ring-opening polymerization of caprolactonc catalyzed by aluminum Iris(isopropoxide) and the product subsequently was used to initiate S polymerization by NMP thus forming polycaprolactone-Woc/r-PS. The alternate strategy of forming PS by NMP and using the hydroxy] chain end of the product to initiate polymerization of caprolactonc was also used. 

Other block copolymers prepared using similar strategies include PEO (anionic) with second block poly(4-vinylpyridine).  

Many examples exist where a polymerization has been continued by ATRP. Often the procedure involves functionalization of a hydroxy-terminated polymer with bromoisobutyroyl (BriBBr, 314) or bromoisopropionoyl (BriPBr, 315) bromide. Examples include poly(ethylene oxide) and poly(propylene 

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