Sebasic acid

The synthetic potentiality of the Kolbe dimerization has been well documented for a variety of symmetrical target molecules. For example, the dimerization of acids (XII and XIII) is the key step of the pentacyclosqualene [55] and o -onocerin [56] syntheses. A large-scale production of sebasic acid has been realized by the Kolbe dimerization of methyl adipate half-ester [57]. 

Nylon 610, not used for textiles, is a copolymer of sebasic acid, COOH(CH,),COOH, and hexamethylene diamine, which finds its outlet in the manufacture of bristles and other monofilaments. Nylon 66-1-6 is... 

Formation of di-esters of dibasic acids. Succinic acid — Adipic acid—Suberic acid—Sebasic acid—n-Dodecane-dicarboxylic acid—n-Decahexane-dicarboxylic acid.37-38... 

PPE, polyanhydrides based on sebasic acid/1,3-bis(p-caboxyphenoxy) propane/... 

Nylon 6-10 1.08 H2N(CH2)6NH2 hexa-methylene diamine HOOCICH IhCOOH sebasic acid —... 

Before 1969, occasional publications reported that sodium 3-(A-allylcu-prothiouredo)-l-benzoate [140, 141] and cuprous iodide [142] had antiinflammatory activity and that Cu(IIXsalicylate)2 had fever-lowering effects [81,82] in various models ofinflammation and fever. In 1969, Bonta [143] and Laroche [144] reported that cupric carbonate (Cu(0H)2CuC03) and cupric complexes of acetic, lauric, oleic, caprylic, butyric, sebasic, lipoic and cinnamic acids [144] were also effective in animal models of inflammation. 

In 1969 a patent of Laroche [82] disclosed that Cu complexes of acetic, lauric, oleic, caprylic, butyric, sebasic, lipoic, and cinnamic acids were orally effective in rats as anti-inflammatory agents at doses corresponding to 18 and 60 mg kg of Cu respectively in the carrageenan paw oedema (CPE) and croton oil granuloma models of inflammation. It was claimed that mixtures of these complexes with clinically used antirheumatic agents would be useful in treating a variety of rheumatic diseases. However, this approach was never used in clinical therapy. 

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