Scytonema mirabile

Tantazoles. Several unusual cytotoxic alkaloids were isolated from the blue-green alga, Scytonema mirabile (Carmeli et al. 1990). A combination of HMQC and HMBC data were utilized in the elucidation of the structure, but no details of the long-range connectivities were given in the paper. The structure of didehydrotantazole-A (47) is shown. The authors comment... 

Carmely S, Ilan M, Kashman Y (1989) 2-Amino imidazole alkaloids from the marine sponge Leucetta chagosensis. Tetrahedron 45 2193-2200 Carmely S, Moore RE, Patterson GML, Corbett TH, Valeriote FA (1990) Tantazoles unusual cytotoxic alkaloids from the blue-green alga Scytonema mirabile. J Am Chem Soc 112 8195-8197... 

C18H26CI4N2O5 M 492.225 Isol. from the terrestrial blue-green alga Scytonema mirabile. Cytotoxic. [a]j) -f 6.5 (c, 0.9 in CHCI3),... 

Some species of the family Scytommataceae produce isotactic polymethoxy-l-olefinic hydrocarbons. It is in the species Tolypothrix conglutinata var. chlorata that the first examples of these polymers were characterized (Mynderse and Moore, 1979), but since then it has been isolated from the species Scytonema mirabile and S. burmanicum. The structures were confirmed by synthesis (Mori, Kohchi, and Suzuki, 1991). 

Tolypothrix conglutinata var. chlorata Scytonema burmanicum, S. mirabile... 

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