Screttas-Cohen process

The first step in the reductive lithiation of alkyl phenyl sulfides (Screttas-Cohen process) consists of preparing the reducing reagent in stoichiometric amounts. Lithium naphthalenide, for example, is made from lithium and naphthalene. The sulfide is added drop wise to this reducing reagent. The mechanism of reduction corresponds step by step to the one outlined in Figure 17.44, except that the dissolved radical anion is the source of the electrons, as opposed... 

Fig. 17.46. Reductive lithiation of an alkyl aryl sulfide (Screttas-Cohen process) and an alkyl chloride (Screttas-Yus process).

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See also in sourсe #XX -- [ ]

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