Screening methods assessment

Nyholm N, P Kristensen (1992) Screening methods for assessment of biodegradability of chemicals in seawater—results from a ring test. Ecotoxicol Environ Saf 23 161-172. 

Use an appropriate atmospheric dispersion model to assess the consequences or risk of each scenario. For screening purposes, atmospheric dispersion models which are less costly may be used to identify the most important scenarios examples are discussed in the following subsection. More expensive modeling procedures can be applied to the most important scenarios provided such procedures are more appropriate and accurate. Screening methods may also be useful in considering the validity of more complicated models. 

This screening method may be used by either a single person or a group of persons. A team approach, involving several persons with different knowledge and functional perspectives, has the possibility of better identifying and assessing the potential for chemical reactivity hazards. 

Procedural controls, process controls, 98-99 Process controls, 96-100 active controls, 98 inherently safer approach, 97 mitigation techniques, 99 passive controls, 97-98 procedural controls, 98-99 safe operating limits, 99-100 Process definition, documentation, 102-104 Process design, documentation, 105 Process hazard analysis (PHA) risk assessment, 92-93 screening methods, 63 Process risk management decisions, documentation, 105-106... 

Lienert J, Gudel K, Escher BI (2007) Screening method for ecotoxicological hazard assessment of 42 pharmaceuticals considering human metabolism and excretory routes. Environ Sci Technol 41 4471 78... 

When defining predictivity criteria, the proposed application of the QSAR should also be taken into account, to accommodate the consequences of making incorrect (or inaccurate) predictions. In principle, QSARs can be used for the priority setting of chemicals, or as components in hazard and risk assessment strategies. In such strategies, QSARs could serve as (partial) replacements of animal experiments, or as screening methods for selecting the experimental tests that need to be conducted. 

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