Schmidt-Druey synthesis

The cyclocondensation of 1,2-diketones, reactive a-methylene esters and hydrazines leads, in its simplest form as a one-pot reaction, to pyridazin-3(2//)-ones 11 (Schmidt-Druey synthesis) ... [Pg.396]

Sandmeyer synthesis (isatin) 145 Schmidt-Druey synthesis (pyridazine) 461 Schollkopf synthesis (oxazole) 173 Sharpless-Katsuki epoxidation 24 Shaw synthesis (pyrimidine) 468 Skraup-Doebner-Miller synthesis (quinoline) 400 Smiles rearrangement 446 Sommelet-Hauser rearrangement 136 Staudinger reaction 53 Steglich reagent (DMAP) 348 Stork isoxazole annelation 191... [Pg.632]

A very useful synthesis of 3(2H)-pyridazinones (18), comprising a multicomponent system, has been developed by Schmidt and Druey. Although the reaction can be performed as a one-step condensation between a 1,2-dicarbonyl compound, an ester with a reactive a-methylene group, and a monosubstituted or unsubstituted... [Pg.228]

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