SbH3 toxicity

The hydrides phosphine PH3, arsine ASH3 and stibine SbH3 can be prepared by hydrolysis of metal phosphates, or by reduction of molecular compounds like PC13. They are very toxic gases, with decreasing thermal stability P > As > Sb. Unlike ammonia they are not basic in water. The hydrazine... 

The most important antimony hydride, stibine, SbH3 is a malodorous, extremely toxic gas (bp -18 °C, mp -88 °C) formed from soluble antimony compounds and hydrogen in... 

Stibine, SbH3, a highly toxic and relatively unstable gas with an unpleasant odor, causes symptoms of the central nervous and circulatory systems, such as nausea, vomiting, headache, slow breathing, weak pulse, hemolysis, hematuria, abdominal pain and death. 

HAZARD RISK Moderate fire hazard in dust and vapor forms reeicts violently with halogens, oxidants, and acids decomposition emits toxic fumes of SbH3 NFPA Code not available. 

EXPLOSION and FIRE CONCERNS moderate fire and explosion hazard in forms of dust and vapor when heated or on contact with acid, emits toxic fumes of SbH3 electrolysis of acid sulfides and antimony halides yields explosive antimony reacts violently with ammonium nitrate, halogens, bromine azide, chloric acid, chlorine oxide, chlorine trifluoride, nitric acid, potassium nitrate, potassium permanganate, potassium peroxide, sodium nitrate, and oxidants use appropriate extinguishing media for firefighting purposes. 

Stibine - SbH3, 7803-52-3 flammable, poison by inhalation bp = -17 C [1 F] er = NA sp g = 4.34 OSHA PEL = 0.1 ppm. Odor similar to hydrogen suUrde but data not available as to whether the odor is an adequate warning of the PEL. Toxic hemolytic agent, which causes injury to hver and kidneys. Probable lung irritant. Symptoms of overexposure may be delayed for up to 2 days and would include nausea, headache, vomiting, weakness, and back and abdominal pain. Death would result from renal failure and pulmonary edema. Baseline medical exam should stress blood, hver, and kidneys. Special tests should include complete blood count, urine analysis, and liver panel. 

Exposure to Sb dust at the place of work over a period of years leads to pneumoconiosis, but this does not develop further than the nodular stage [26,27]. Stibine (SbH3) has the highest toxicity of any Sb compound and has a more intense and rapid effect than the corresponding As compound [28,29], even though Sb compounds are generally less toxic than arsenic and its derivatives. 

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