Saturated Heterocyclic Ring Synthesis

The aim of this Report is to review new methodology for the synthesis of saturated heterocyclic compounds. Emphasis is placed on reactions which involve a cyclization step and few ring transformations are described. Heterocycles which contain phosphorus, selenium, and silicon as the heteroatom are omitted. A few key steps in complex natural product syntheses are mentioned, but carbohydrates are excluded. The rapidly increasing numbers of reports describing the synthesis of saturated and unsaturated lactones and of crown ethers are covered in Chapters 3 and 10. 

Baldwin has proposed that the term stereocontrolled synthesis should describe a stereospecific synthesis that as a result of bond forming reactions provides only the desired stereochemistry, without a need for subsequent epimerization. 

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Saturated Heterocyclic Ring Synthesis , W. J. Ross, in General Synthetic Methods, ed. 

Saturated Heterocyclic Ring Synthesis only in very poor yields. 

The decrease in size of the present volume relative to Volume 1 is mainly due to a tightening up in the presentation of the subject matter which is covered. The Reporters have attempted to achieve this end whilst still maintaining a comprehensive and a critical commentary. The decrease in size is also due to the omission of a chapter on Saturated Heterocyclic Ring Synthesis it is intended to remedy this unfortunate omission in Volume 3. We also plan to include a special review in Volume 3 covering the important recent developments in the utilization of Photochemistry in Synthesis . 

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