SAR of Fibers, Particles, and Nanomaterials

Group 2B. Possibly Carcinogenic to Humans Refractory ceramic fibers 

Special purpose glass fibers (e.g., E-glass microfibers) 

Group 3. Not Classihable as to their CARaNOGENiaTY Glass wool 

Continuous glass filament Rock (stone) wool Slag wool Para-Aramid Wollanstonite Sepiolite 

Direct genotoxic and mitogenic effects of asbestos, as well as of some manmade fiber s, have been detected in in vitro assays [e.g., (Dopp et al. 1997 Osgood 1994 Wang et al. 1999)]. The physical presence of phagocytosized fibers can interfere with chromosome segregation during mitosis and result in aneuploidy and 

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