Sappho technology

SAPPHO technology which combines a modular approach to synthesis with an innovative solubilisation system guarantees ... 

Different coupling reagents such as N-hydroxysuccinimide activated esters of amino acids, T.B.T.U. ((0-1 H-benzotriazol-1 -y 1)-1,1,3,3-tetramethy 1-uronium tetrafluoroborate), or N protected N carboxyanhydrides of amino acids (UNCA), and so on can be used in the SAPPHO technology. 

SAPPHO is a powerful new innovative technology for the automated large scale synthesis of peptides in solution phase, which can lead to significant cost saving of up to 50 % compared to the traditional technologies (in homogeneous phase or Merrifield phase). 

We have demonstrated that the SAPPHO process is a new and powerful method of synthesizing peptides, at a low cost, with very good yield and purity. It is the first automated peptide synthesis technology which can be used to synthesize peptide or peptide fragments from 3 to 15 aminoacids. 

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