SANT domains

In addition protein domains have been identified which bind to modified histone tails. The so-called bromodomains bind to acetylated histone tail, but have little or no affinity to unmodified tails. Further known binding domains include chromodomains and SANT domains which possess preferential binding to methylated and unmodified tails. 

Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-Ll. J. Biol. Chem. 276, 6817-6824. 

Baker AM, Fu Q, Hayward W, Lindsay SM, Fletcher TM. The Myb/SANT domain of the telomere-binding protein TRF2 alters chromatin stracture. Nucleic Acids Res. 2009 37 5019-31. 

Boyer, L.A. Latek, R.R. Peterson, C.L. (2004). The SANT domain a unique histone-tail-binding module Nature Reviews Molecular Cell Biology, Vol.5, No.2, (February 2004), pp. 158-163, ISSN 1471-0072... 

SANT SW13, ADA2, N-CoR and TFIIIB, DNA-binding domains E(MFP)B 18(31) 18(31) 1A5J... 

C. HAT Complex Proteins Contain RING, SANT, and PHD Domains. 190... 

Ryan DP, Sundaramoorthy R, Martin D, Singh V, Owen-Hughes T. The DNA-binding domain of the Chdl chromatin-remodeling enzyme contains SANT and SLIDE domains. EMBO J. 2011 30 2596-609. 

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