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Sanorex - Mazindol

Sanorex (Mazindol). Novartis Pharmaceuticals. Canadian prescribing information. Compendium of Pharmaceuticals and Specialities, 2004. [Pg.1138]

Mazindol (Sanorex) (hydrochloride), 3 91, 92t Mazu, commercial defoamer, 8 24 It m-base dyes, 9 474 MBS polymers, 16 290 McBee-Hass chlorination technique, 16 322 McCabe—Thiele diagram... [Pg.556]

Mazindol (Sanorex) produces typical amphetaminelike anorexia and CNS stimulation. The drug inhibits NE uptake in a manner identical to the tricyclic antidepressants. Its very potent appetite suppressant ability was found while being evaluated as an antidepressant. Mazindol does not contain the P-phenethylamine foundation within its frame. It is structurally the enol form of an imidazole-substituted benzophenone, probably in equilibrium with its isoindole form (Eq. 9.12) in solution. [Pg.411]

MazindoL 5 <4 Chtorophenyth2r5-dihydro 3H imidazo[2rl-aiisoindoi-5-ol 5. 4-chlorophenyl)-2.3-dihy-dro-5-hydroxy-5//-imidazo[2, l -ojisoindole SaH 42548 Dimagrir Magrilon Mazildene Sanorex Terenac Teronac. [Pg.903]

Mazindol (Sanorex ) is a phenyl-substituted imidazobenzoisoindole that inhibits both NE and dopamine reuptake transporters. It exhibits high affinity for the NET (rat pKj = 9.3), good affinity for dopamine transporter (rat pKj = 7.8), and a 5-HT NE ratio of 224. Dopamine reuptake inhibitors suppress appetite thus, mazindol is approved to be marketed as an appetite suppressant. [Pg.860]

See other pages where Sanorex - Mazindol is mentioned: [Pg.1739]    [Pg.364]    [Pg.75]    [Pg.1739]    [Pg.1739]    [Pg.1739]    [Pg.364]    [Pg.75]    [Pg.1739]    [Pg.1739]    [Pg.37]    [Pg.342]    [Pg.1416]    [Pg.153]    [Pg.163]    [Pg.723]    [Pg.172]    [Pg.29]    [Pg.402]    [Pg.5]   


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