Sampling, artifacts noise

The availability of pulsed field gradient (PEG) techniques has had the most significant impact in terms of making it possible to perform 2D- and 3D-NMR experiments on polymer samples. These methods have taken the place of traditional radiofrequency phase cycling methods for coherence selection. By optimizing the use of the spectrometer s dynamic range, PEG techniques not only save time but also drastically reduce artifact noise. 

Unfortunately, real data is never as nice as this perferctly linear, noise-free data that we have just created. What s more, we can t learn very much by experimenting with data like this. So, it is time to make this data more realistic. Simply adding noise will not be sufficient. We will also add some artifacts that are often found in data collected on real instruments from actual industrial samples. 

Of all the requirements that have to be fulfilled by a manufacturer, starting with responsibilities and reporting relationships, warehousing practices, service contract policies, airhandUng equipment, etc., only a few of those will be touched upon here that directly relate to the analytical laboratory. Key phrases are underlined or are in italics Acceptance Criteria, Accuracy, Baseline, Calibration, Concentration range. Control samples. Data Clean-Up, Deviation, Error propagation. Error recovery. Interference, Linearity, Noise, Numerical artifact. Precision, Recovery, Reliability, Repeatability, Reproducibility, Ruggedness, Selectivity, Specifications, System Suitability, Validation. 

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