Saliva, Organic volatiles

Gas Chromatography of Organic Volatiles in Human Breath and Saliva Acta Chem. Scand. 19(1) 159-164 (1965) CA 62 15050g... 

New York Developing capacity to monitor for polyaromatic hydrocarbons (PAHs) in urine, polybrominated diphenyl ethers (PBDEs) in serum, organochlorine pesticides in serum, volatile organic compounds (VOCs) in blood, cotinine in saliva, trace elements in blood and urine, inorganic mercury in blood and to generate data on exposure to persistent organic pollutants (CDC 2005). 

Some toxic agents such as Pb, Hg, other heavy metals, and many organic substances are excreted in the bile as conjugates to the intestinal tract for elimination in the feces. Other common routes of elimination include the lungs for gaseous (e.g., NH3) and volatile toxicants (e.g., alcohol, sweat, tears, and saliva), as well as breast milk and eggs in females. 

The organism eliminates toxic substances or their metabolites through the kidneys, bile, lungs, saliva, stools and skin. The excretion by the kidneys is of the main importance. This mechanism is the same as that during the excretion of final products of primary and secondary metabolic pathways. Substances absorbed in the gastrointestinal tract are eliminated from the blood by the liver. These substances can be removed by the liver prior to reaching the circulation system. Substances which enter the body by inhalation are also eliminated from the lung (carbon monoxide, alcohol, volatile substances). The excretion system is not specialized and it operates on the basis of a simple diffusion [7-9]. 

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