Saccadic impairment

Saccades are also affected by anticholinergic hallucinogens in humans (Oliva et al. 1993). Increases in saccade duration and latency occur along with decreases in velocity. Postsaccadic fixation is impaired as well, where the eye drifts after reaching the target. 

Oliva GA, Bucci MP, Fioravanti R. (1993). Impairment of saccadic eye movements by scopolamine treatment. Percept Motor Skills 159-67. 

Motor, executive functions Slower saccades. Some impairment, especially in complex tasks No effect... 

Similar results have been forthcoming from primate studies. Thus, D1 receptor antagonists administered iontophoretically to the PFC enhance, rather than impair, stimulus processing by single units in delayed saccade paradigms (Williams and Goldman-Rakic,... 

Alcohol clearly affects eye movement. Both smooth pursuit movements and saccades are impaired when blood ethanol concentrations reach the range of 60 to 100 mg/dl. There is a direct linear relationship between blood alcohol concentration and a reduction in smooth-pursuit movement velocity. At a blood ethanol concentration of 80 mg/dl, the capacity of the eyes to track objects moving across the visual fields is impaired by 25%. 

Findings Impaired Halstead Impairment Index, rotational testing, asymmetry of saccadic velocity, and somatosensory evoked potentials... 

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