S-ofloxacin

S-Ofloxacin is an optically active fluorinated quinolone with antibacterial properties. U.S. 5,053,407 describes the preparation of the API. Estimate the cost of production of this compound. Which stages of the process would you operate in batch mode and which stages would you operate continuously ... 

Ofloxacin rr 0 I I I COOH Human medicine - High levels in hospital WW [4,5] It s strongly sorbed onto soil. Persistent in the environment [1]... 

As is discussed at a later point in this review, it has been shown that the enantiomer (33) of ofloxacin [81] and the related enantiomer (34) of S-25930 [82] are each significantly more potent antibacterial agents than their respective enantiomers furthermore, the gem-dimethyl analogue (35) is as inactive as the... 

J.Y. Shen, M.R. Kim, C.J. Lee, I.S. Kim, K.B. Lee and J.H. Shim, Supercritical fluid extraction of the fluoroquinolones norfloxacin and ofloxacin from orally heated chicken breast muscles. Anal. Chim. Acta 513 (2004) 451-455. 

It is the levoisomer of ofloxacin and having better activity than ciprofloxacin and ofloxacin against S. pneumoniae. It is also used in chronic bronchitis, sinusitis, pyelonephritis, and other related infections of soft tissues. Due to high oral bioavailability, patient can be shifted from IV to oral therapy. It can be administered just once a day regimen as an alternate to other fluoroquinolones in the treatment of respiratory infections. 

---