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Ruthenium anticancer agents/drugs

In our group, a major part of our research is devoted to the design of new anticancer drugs. Our recent efforts towards the discovery of new platinum-, ruthenium- and osmium-based anticancer agents provide the topic for this account and a section is devoted to each metal. We focus on recent results from our lab in the context of other developments and related research in this field (hence our coverage of the field is focused on these areas and is not comprehensive). [Pg.2]

Intercalative binding to DNA is often proposed as a route to enhancing selectivity of anticancer agents, and shape-selective intercalation of ruthenium-polyaromatic amines has been widely used for probing DNA structure (185). This approach could yield new drugs. [Pg.214]

Alessio E, Mestroni G, Bergamo A, Sava G (2004) Ruthenium anticancer drugs. In Sigel H (ed) Metal Complexes in Tumor Diagnosis and as Anticancer Agents. CRC Press, USA, pp 323-351... [Pg.49]

See other pages where Ruthenium anticancer agents/drugs is mentioned: [Pg.319]    [Pg.2]    [Pg.22]    [Pg.44]    [Pg.48]    [Pg.50]    [Pg.57]    [Pg.292]    [Pg.348]    [Pg.67]    [Pg.348]    [Pg.371]    [Pg.13]    [Pg.451]    [Pg.7]    [Pg.119]    [Pg.164]    [Pg.581]    [Pg.605]    [Pg.21]    [Pg.667]    [Pg.87]    [Pg.57]    [Pg.384]    [Pg.759]    [Pg.3]    [Pg.158]    [Pg.121]    [Pg.48]    [Pg.585]    [Pg.266]    [Pg.299]    [Pg.555]   
See also in sourсe #XX -- [ Pg.164 ]



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