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Rodent monoclonal antibodies

More than twenty years of rodent monoclonal antibody generation by the classical hybridoma technology has yielded a number of promising therapeutic candidates and their humanization compares well to the de novo generation and characterization of human antibodies for accessing clinical applications in the coming years. [Pg.324]

Other rodent monoclonal antibodies against cell membrane markers (CD molecules) have been described. The adverse effects of such antibodies can be ascribed to the general adverse effects of a heterologous protein, or to effects of the cell-targeting mechanisms (for example cell lysis). [Pg.2381]

Preparation of rodent monoclonal antibodies by in vitro somatic hybridization... [Pg.1]

See other pages where Rodent monoclonal antibodies is mentioned: [Pg.59]    [Pg.59]    [Pg.34]    [Pg.250]    [Pg.2381]    [Pg.2381]    [Pg.1]    [Pg.3]    [Pg.5]    [Pg.7]    [Pg.9]    [Pg.11]    [Pg.13]    [Pg.15]    [Pg.17]    [Pg.19]    [Pg.21]    [Pg.23]    [Pg.1]    [Pg.3]    [Pg.5]    [Pg.7]    [Pg.9]    [Pg.11]    [Pg.13]    [Pg.15]    [Pg.17]    [Pg.19]    [Pg.21]    [Pg.23]   


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