Ribose Ribosomal-inactivating

Poly(ADP-ribose) polymerase homology to other proteins. Sequence similarity comparison of the polymerase with the National Biomedical Center s protein data bases revealed no extensive identities with other proteins (> 4200 proteins searched). Although no extensive similarities were observed, the polymerase exhibits some short but interesting identities. The most statistictdly significant identity is with the catalytic site of the ricin A chain, a cytotoxic plant protein which inactivates the 60S ribosome. This may represent the active site of the enzyme, based upon the catalytic... 

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