Asymmetric transfer hydrogenation rhodium catalysis

Gladiali, S., Pinna, L., Delogu, G., De Martin, S., Zassinovich, G., Mestroni, G. Optically active phenanthrolines in asymmetric catalysis. III. Highly efficient enantioselective transfer hydrogenation of acetophenone by chiral rhodium/3-alkyl phenanthroline catalysts. Tetrahedron Asymmetry 990, 1, 635-648. 

There have been several examples of multi-phase systems in asymmetric syntheses, notably a polymeric chiral rhodium hydrogenation catalyst for selectively producing i -amino-acids, and the use of phase-transfer catalysis in asymmetric carbon-carbon bond formation. The incorporation of optically active cinchona alkaloids, e.g. quinine (29), into a polymer by virtue of their vinyl group has been described, with preliminary results on application to asymmetric syntheses. At the other extreme of structural complexity, enzymes themselves have been incorporated into polymers to some advantage. ... 

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