Rhenium nuclear properties

Rhenium complexes containing the metal in the oxidation state +III are comparatively numerous. This may be ascribed to the fact that the d configuration of the rhenium center can readily be stabilized by ligands with pronounced donor and rr-acceptor properties. Most of the rhenium(III) compounds are stable against hydrolysis rendering them suitable for nuclear medical applications. 

The chemistry of rhenium(I) is dominated by organometallic compounds which are not covered by this review. Thus, cyclopentadienyl and related compounds, where the organometallic part of the molecule dominate the properties will generally not be considered. Nevertheless, compounds with carbonyl or isocyanide co-ligands will be treated when they can be regarded as constituents of a typical coordination compound or the compounds are of fundamental interest in a radiopharmaceutical context such as the hexakis(isocyanide)rhenium(I) cations. For the same reason a separate section has been included which gives a brief summary of recent attempts to develop synthetic routes to tiicarbonylrhenium(I) complexes for nuclear medical applications. 

The coordination chemistry of rhenium is better known and easier to handle than that of technetium and, in view of their expected analogies, the former metal can be used for nonradioactive model studies for technetium. In addition, Re and Re display attractive properties (Section 1) for nuclear medicine. The biolocalizations of analogous Re and Tc compounds can also be similar. Hence, the Tc and the Re (or Re) radionuclides constitute a potential matched pair for diagnosis and therapy. ... 

The knowledge of the chemical properties of technetium has grown over the years, as indicated hy review articles and books (Dewanjee 1990 Lever 1995 Nowotnik 1994 Peacock 1966 Schwochau 1983 Steigman and Eckelman 1992). Of particular interest are the Proceedings of the International Symposium on Technetium in Chemistry and Nuclear Medicine, presenting new developments in complex chemistry of technetium and rhenium, with state-of-the-art lectures, listed at the end of this chapter under Further Reading . 

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