Retrosynthetic schemes for

On the basis of the preceding discussion the reader should be able to derive retrosynthetic schemes for the construction of targets 6, 7, and 8 based on the Diels-Alder transform. 

Fig. 33 General retrosynthetic scheme for imino sugars synthesis.

Synthesis. Outline a retrosynthetic scheme for each of the following target molecules using the indicated starting material. Show (1) the analysis (including FGI, synthons, and synthetic equivalents) and (2) the synthesis of each TM. 

SCHEME 4. Retrosynthetic scheme for the synthesis of the GPI-anchor of T. cruzi trypomastigote glycoproteins, lacking Gal/ in the glycan, showing key building blocks and D-mannose monosaccharide intermediates. 

Figure 10.23. MARSEIL-SOS generated retrosynthetic scheme for turmerone.

Scheme 1.1 Two (of many conceivable) retrosynthetic schemes for callystatin A, a cytostatic compound of limited natural supply...

The two retrosynthetic schemes for callystatin A reveal significant differences. In Scheme A, the cuts are done to separate the target into pieces of roughly similar size. By contrast, in Scheme B, the cuts have been done at tbe periphery of the target structure thus failing to provide optimal retrosynthetic simplification. 

This approach appears to be attractive first and foremost because it is Nature s way to synthesize proteins on the ribosomes. Furthermore, as the mere inspection of the retrosynthetic scheme for angiotensin shows... 

Scheme 10.7 Retrosynthetic schemes for cnnstmction of 2..3-epoxy alcohols.

The following is a retrosynthetic scheme for the preparation of trans-2-allylcyclohexanol. Show reagents to bring about the synthesis of this compound from cyclohexane. 

Following is a retrosynthetic scheme for the synthesis of the tricyclic diene on the left. Show how to accomplish this synthesis from 2-bromopropane, cyclopentadiene, and 2 - cyclohexenone. 

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