Retrochalcone Echinatin

FIGURE 3.5 Biosynthetic route to isoflavonoids (and some derivatives) from the 5-deoxyflavanone liquiritigenin. A possible route to the retrochalcone echinatin is also shown. Unlabelled arrows indicate biosynthetic steps for which the enzyme(s) have not been characterized. Enzyme abbreviations are defined in the text and in Table 3.1, except for P2CP, pterocarpan 2-C-prenyltransferase P4CP, pterocarpan 4-C-prenyltransferase. 

Ayabe, S. and Furuya, T., Studies on plant tissue cultures. Part 36. Biosynthesis of a retrochalcone, echinatin, and other flavonoids in the culture cells of Glycyrrhiza echinata. A new route to a chalcone with transposed A- and B-rings, J. Chem. Soc. Perkin Trans. 1, 2725, 1982. 

Ayabe, S., T. Yoshikawa, M. Kobayashi, and T. Furuya Studies on Plant Tissue Culture. 34. Biosynthesis of a Retrochalcone, Echinatin Involvement of O-Methyl-transferase to Licodione. Phytochem., 19, 2331 (1980). 

Saitoh, T. et al., Biosynthesis of echinatin. A new biosynthetical scheme of retrochalcone. Tetrahedron Lett., 16, 4463, 1975. 

Saitoh, T, S. Shibata, U. Sankawa, T. Furuya, and S. Ayabe Biosynthesis of Echinatin. A New Biosynthetical Scheme of Retrochalcone. Tetrahedron Letters, 1975, 4463. 

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