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Retinoid analysis mass spectrometry

Furr, H C, Clifford, A J., and Jones, A D (1992) Analysis of apocarotenoids and retinoids by capillary gas chromatography-mass spectrometry Methods Enzymol. 213,281-290. [Pg.28]

A wide variety of liquid chromatography-mass spectrometry (LC-MS) techniques have been reported for retinoid analysis including direct liquid introduction with Cl (281,282,299-301), particle beam (302-304), thermospray (305-307), electrospray (308,309), and atmospheric pressure chemical ionization (APCI) (310). Because many of the early LC-MS applications to retinoids carried out hydrolysis of retinyl esters and then derivatization of retinoic acid and related retinoids, Wyss (141) predicted in a review of retinoid analysis that derivatization of retinoids would be necessary for all LC-MS techniques, even the anticipated application of atmospheric pressure chemical ionization (APCI). Recently, LC-MS analyses of retinoids have been carried out using APCI (310) and electrospray (308,309), and highly sensitive LC-MS analyses of retinoic acid and retinyl esters were achieved without hydrolysis or derivatization. [Pg.54]

See other pages where Retinoid analysis mass spectrometry is mentioned: [Pg.221]    [Pg.359]    [Pg.699]    [Pg.439]    [Pg.447]    [Pg.20]    [Pg.52]    [Pg.53]    [Pg.55]    [Pg.58]    [Pg.65]    [Pg.65]   
See also in sourсe #XX -- [ Pg.221 , Pg.222 , Pg.223 , Pg.224 ]



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