Results of Aqueous Solubility Determined from A Shifts

5 Results of Aqueous Solubility Determined from A Shifts 

Since the pKa values of the compounds studied are reliably known (Table 6.1), it was possible to calculate the A shifts (Table 6.2). These shifts were used to calculate the corrected aqueous intrinsic solubilities So, also listed in Table 6.2. 

TABLE 6.2 True Aqueous Solubility Determined from pKa Shifts of Monoprotic Compounds 

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