Restricted synchrony

Fig. 21. Free-running synchrony by four heat shocks (upper continuous curve) and restricted repetitive synchrony by four to five heat shocks (upper continuous curve extended by dashed curve). Results of electronic cell counts and of chemical analyses refer to the restricted system at the end of shock 5 (7.2 x 10 cells/ml) DNA 12.5 RNA 344 protein 3,330 ju/ig/cell. Tetrahymena cells synchronized repetitively and under restricted conditions are of almost the same size as are normally growing cells. This will be apparent from comparison of the figures just presented with those in the legend accompanying Figure 11 in the review by Zeuthen Rasmussen, 1971.

In pressure ventilation, most ventilators cycle from inspiration to expiration when inspiratory flow decreases to a predetermined percent of its peak flow or when a preset inspiratory time is reached. It has become increasingly clear that cycling plays an important role in assuring patient-ventilator synchrony (11). This has been quite well studied in pressure support ventilation and several authors have shown that a fixed cycle value can lead to premature cycling in patients with restrictive diseases and delayed cycling in those with obstructive disease (12,13). 

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