Restlessness methylphenidate

Comparative trials Non-stimulant medications are being evaluated for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents as alternatives to stimulants. In these studies reduced appetite and restlessness were more common with methylphenidate than with amantadine [54 ], and headache and insomnia were more common with methylphenidate than with venlafaxine [55 ]. Nevertheless, these studies do not constitute proof of efficacy. 

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