Renshaw inhibitory system

Certain intemeurons located in the anterior horn in close association with the motor neurons constitute the Renshaw inhibitory system, which causes inhibition of neurons surrounding the motor neuron carrying a given excitatory impulse. This phenomenon is known as recurrent inhibition. The function of the Renshaw inhibitory system is to sharpen the signal of the motor rmit It prevents the signal from diffusing into adjacerrt nerve fibers, which wotrld weaken the signal. 

In vertebrates, most of the central neurons are neither cholinergic nor cholino-ceptive. In the spinal cord only the synapses formed by the collaterals of the motoneuron axons on the Renshaw cells have proved to be cholinergic. These synapses are part of the self-inhibitory system of motoneurons. Each impulse being pro-... 

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