Removal of Methoxybenzyl Protective Group

Because the compared protective groups in phenylalanine also differ in their electron acceptor activity, one can expect that anion-radical generation would result in the selective removal of amine protection. This assumption is supported by the ESR studies of some peptide cation-radicals (Lin et al. 1998). For instance, neat histone (a protein from cell nuclei) gives an anion-radical in which the unpaired electron is localized at the amidocarbonyl function. 

Ion-Radical Organic Chemistry Principles and Applications OSiMes 

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