Release of Lipid from Adipose Tissue Stores

Release of Lipid from Adipose Tissue Stores 

During fasting or exercise and at times of stress, lipid is used as a source of energy. Hormone-sensitive lipase catalyzes the sequential hydrolysis of triacylglycerol to 

Norepinephrine Glucagon ACTH Secretin Vasopressin Growth hormone Prostaglandin E j 

Regulation of adipocyte triacylglycerol synthesis and degradation. FA, Fatty acid PDF, phosphodiesterase. 

As fatty acids leave the adipocyte, they form complexes with albumin. The availability of separate pathways for fat deposition and release in these cells permits appropriate regulation under anabolic or catabolic circumstances. The absence of glycerol kinase in the adipocyte decreases the potential for resynthesis of the triacylglycerol and promotes hepatic gluconeogenesis. Triacylglycerols are deposited in the adipocyte when glucose and insulin are readily available. 

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