Related Toxicity Often Occurs When Impaired Renal Function is Unrecognized

Dose-Related Toxicity Often Occurs When Impaired Renal Function is Unrecognized 

Failure to appreciate that a patient has impaired renal function is a frequent cause of dose-related 

TABLE 1.1 Status of Renal Function in 44 Patients with Digoxin Toxicity  

Serum creatinine (mg/dL) No. of patients with CLcji of 50 mL/min 50 mL/min Percentage of group 

Holmstedt B, Liljestrand G. Readings in pharmacology. Oxford Pergamon 1963. 

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