Refusal training

The social pressures to abuse drugs or drink call for specific assertive responses in relation to these substances. Foy et al. (1976) developed a technique called refusal training for such instances. The components of a refusal response are ... 

Foy, D.W., Miller, P.M., Kislcr, R.M., and O Toole, D.H. (1976) Social skills training to teach alcoholics to refuse drinks effectively Journal of Alcohol Studies, 37 1340-5. 

Many male pharmacists still refused to take on women apprentices. One of the major boosts for training women in pharmacy was a single chemist s shop Number 17, The Pavement, Clapham Common.40 The pharmacy had been opened by Henry Deane in 1837. Deane had joined the Pharmaceutical Society in 1841, being one of its earliest members, and he was President from 1853 until 1855. The pharmacy was purchased sometime between 1911 and 1914 by Buchanan as a training facility for women. She was joined in 1914 by Agnes Borrowman (see below). One of their student intake of 1915 recalled ... 

A 72-year-old woman with a symptomatic hiatus hernia, osteoarthritis, and Alzheimer s disease was taking fluoxetine 20mg/day, donepezil hydrochloride 10 mg/ day, nimesulide 12.5mg/day, and omeprazole 20 mg/ day (288). There still was no twitch response to peripheral nerve stimulation 20 minutes after rapid-sequence induction of anesthesia with propofol 2.5mg/kg and suxamethonium 1 mg/kg. She then gradually developed a weak twitch response, and 50 minutes after induction of anesthesia four twitches with a fade were elicited by train-of-four stimulation. No additional medication was given and after the end of the procedure 10 minutes later she was extubated uneventfully. She refused further blood testing and so her plasma cholinesterase activity at that time is not known. However, her anesthetic notes from a previous operation did not reveal any problems with prolonged paralysis after suxamethonium. 

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