Reed, Randall

Biochemical studies in the late 1980s examined isolated cilia from rat olfactory epithelium that had been treated with odorants. Exposure to the odorants increased the cellular level of cyclic AMP, and this increase was observed only in the presence of GTP. On the basis of what was known about signal-transduction systems, the participation of cAMP and GTP strongly suggested the involvement of a G protein and, hence, 7TM receptors. Indeed, Randall Reed purified and cloned a G-protein a subunit, termed... 

Linn, T.C. Pelley, J.W. Pettit, RH. Hucho, R Randall, D.D. Reed, L.J. a-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart. Arch. Biochem. Biophys., 148, 327-342 (1972)... 

Kitajima, N. Tamura, N. Amagai, H. Fukui, H. Moro-oka, Y. Mizutani. Y. Kitagawa, T. Mathur. R. Heerwegh, K. Reed, C.A. Randall, C.R. Que, L., Jr. Tatsumi, K. Monomeric carboxylate ferrous complexes as models for the dioxygen binding-sites in non-heme iron proteins The reversible formation and characterization of p-peroxo diferric complexes. J. Am. Chem. Soc. 1994,... 

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