REDUCTIVE ANNULATION OF VINYL SULFONES

Reductive Annulation of Vinyl Sulfones. Bicyclo[4. 3. 0]hon-l-en-4-one H.-S. Lin and L. A. Paquette, Department of Chemistry, The Ohio State University, Columbus, OH 43210... 

As a group, annulation reactions have been exceedingly valuable to the synthetic organic chemist. Unfortunately, processes of this type involving simple alkenes and cycloalkenes are few. However, the facility with which unactivated olefins can be transformed into vinyl sulfones, the high degree to which a, 8-unsaturated sulfones are captured regioselectively by unsymmetrical dienes such as those developed by Danishefsky, and the ease with which reductive desulfonylation can be effected, combine to permit convenient synthetic entry to substituted cyclohexenones. Several representative examples can be found in Table 1. 

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