Reduction known genome data

Screening of a library of overexpressed enzymes from a microorganism with known genome data is useful for searching a catalyst for a desired reaction. For example, enantio- and diasteieoselective reduction of ethyl 2-chloro-3-oxoalkanoates was investigated using a reductase library (18 known and putative enzymes) from baker s yeast expressed in Escherichia coli (Scheme 33.1a). It was... 

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