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Recombinant human deoxyribonuclease rhDNAse

Chan, H.-K. Clark, A. Gonda, I. Mumenthaler, M. Hsu, C. Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery. Pharm. Res. 1997, 14, 431-497. [Pg.1433]

Chan, H.-K. Gonda, 1. Solid state characterization of spray-dried powders of recombinant human deoxyribonuclease (rhDNase). J. Pharm. Sci. 1998, 87, 647-654. [Pg.1655]

Warming may have a beneficial effect. For instance, the temperature of fluids atomized in air-jet nebulizers decreases by approximately 10-15°C during use, resulting in bronchoconstriction in some asthma suffers.Bronchoconstriction, which is most marked at 5°C, disappears at 37°C and thus may be minimized by using an ultrasonic device. Furthermore, when solutions of drugs with low solubility are to be nebulized, ultrasonic nebulizers, which warm the solutions, may be preferable to air-jet devices, which cool them and may cause precipitation. However, the heat generated may harm heat-labile materials such as diethylenetriaminepentoacetic acid ( mTc-/DTPA), " proteins, and some antibiotic solutions. Thus, ultrasonic nebulizers are specifically prohibited for aero-solization of recombinant human deoxyribonuclease (rhDNase). ... [Pg.3858]

Green, J.D. Pharmacological-toxicological (expert report on recombinant human deoxyribonuclease I (rhDNase pulmo-zyme ). Human Experimental Toxicology 1994, 13, S1-S42. [Pg.1286]

Fig. 1 An example of excipient as carrier for drug particles. Scanning electron micrographs showing adhesion of recombinant human deoxyribonuclease I (rhDNase) particles to lactose (A) and mannitol (B). Fig. 1 An example of excipient as carrier for drug particles. Scanning electron micrographs showing adhesion of recombinant human deoxyribonuclease I (rhDNase) particles to lactose (A) and mannitol (B).
Cipolla, D.C. Clark, A.R. Chan, H.-K. Gonda, I. Shire, 59. S.J. Assessment of aerosol delivery systems for the recombinant human deoxyribonuclease I (rhDNase). STP Pharma Sciences 1994, 4, 50-62. [Pg.2740]

PULMOZYME (Dornase Genentech alfa) [(CHO-expressed recombinant glycoprotein-human deoxyribonuclease I (rhDNase)]... [Pg.326]

See other pages where Recombinant human deoxyribonuclease rhDNAse is mentioned: [Pg.383]    [Pg.2731]    [Pg.668]    [Pg.383]    [Pg.2731]    [Pg.668]    [Pg.260]    [Pg.1650]    [Pg.451]    [Pg.347]    [Pg.521]    [Pg.696]   
See also in sourсe #XX -- [ Pg.383 ]

See also in sourсe #XX -- [ Pg.1650 , Pg.3858 ]



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Deoxyribonuclease

Deoxyribonucleases

Recombinant human

Recombinant human deoxyribonuclease

RhDNase

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