Recognition site points

Two points need to be emphasized concerning the data on ACh release. First, PCP, etoxadrol, and cyclazocine are very potent, being effective in the same range in which they compete with 3H-PCP for binding to the PCP/sigma receptor recognition site. 

Table 3.2 Some commercially available REs, their sources, DNA recognition sites and cleavage points... 

The concept of a defect has undergone considerable evolution over the course of the last century. The simplest notion of a defect is a mistake at normal atom site in a solid. These stmcturally simple defects are called point defects. Not long after the recognition of point defects, the concept of linear defects, dislocations, was invoked to explain the mechanical properties of metals. In later years, it became apparent that planar defects, including surfaces, and volume defects such as rods, tubes, or precipitates, also have important roles to play in influencing the physical and chemical properties of the host matrix. More recently, it has become apparent that interactions between point defects are of considerable importance, and the simple model of isolated point defects is often inadequate with... 

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