Receptors for Other Picornaviruses

Receptors for Other Picornaviruses A. Foot-and-Mouth Disease Vims 

There are seven serotypes of FMDV (O, A, C, Asia, SATl, SAT2, and SAT3) and although most utilize integrins for cell entry, certain strains of Oi FMDV have been shown to use HS as the predominant cell surface ligand (Jackson et al, 1996). For these strains of FMDV, attachment to HS is highly specific and is required for efficient infection. Crystal structures have been published of the FMDV strain OiBFS complexed with various 

---