Receptor Agonist/antagonist bound

The use of structure-based virtual screening toward novel nuclear hormone receptor antagonists was described by Schapira et al. [263]. As only X-ray structures of ligand binding domains of agonist-bound nuclear receptors with exception of the antagonist-bound estrogen receptor-a are available, the authors constructed an inactive ... 

Antagonist bound to the the postsynaptic receptor, inhibiting an agonist from interacting at this receptor site... 

POTENTIAL USEFULNESS OF CELL MEMBRANE-BOUND ENZYME SUBSTRATES AND INHIBITORS, AND CELL MEMBRANE-BOUND RECEPTOR AGONISTS AND ANTAGONISTS AS DRUG CARRIERS WITH LUNG SPECIFICITY... 

Thus, when t noncompetitive antagonism will result. This is the opposite extreme of the case for simple competitive antagonism discussed in Section 6.3. 

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