Reactor 16 Integrated Micro Laboratory Disk Synthesizer

Reactor 16 [R 16] Integrated Micro Laboratory Disk Synthesizer 

This type of integrated chemical synthesizer comprises a device array of micronsized wells and connecting channels in a substrate that interfaces with a station for dispensing fluids to and collecting fluids from the array and for performing analytical measurements of material in the well. The station is also connected to control apparatus to control the fluid flow to the channels and wells and to collect measurement data from the substrate. All the mentioned elements are independent and together they can perform a variety of tasks in parallel [85], 

The array is formed in a suitable dielectric substrate and the channels and wells are formed therein using maskless semiconductor patterning techniques. The station and control means, such as computer, use existing technology that includes commercially available apparatus [85], 

In addition to clinical and biochemical reactions, e.g. DNA analysis, immunological assays or syntheses of large number of oligomers and peptides, comparably small molecules can be synthesized. The synthesis of an array of different substituted 1,4-benzodiazepine compounds is claimed [85], 

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