Reactions Catalysed by Simple Cationic Micelles

Reactions Catalysed by Simple Cationic Micelles.— There have been important recent developments in our understanding of nucleophilic catalysis in micelles. The main credit in this must go to Romsted, whose PhD thesis contains the analysis now generally accepted to be the best available description, and which is more readily accessible in a review article. It is a pseudo-phase model, which is superior to earlier approaches because it makes specific allowance for ion-dissociation and ion-exchange at the micelle surface. The derived equation for a second-order reaction is  

Politi, I. M. Cuccovia, S. M. Martins-Franchetti, and H. Chaimovich, J. Phys. 

Few studies of amide hydrolysis have been carried out under conditions of micellar catalysis. Gani and Viout find that there is weak acceletation of the hydrolysis of activated amides (cturying electron-withdrawing alkyl groups or anion-stabilizing N-substitutents) by cetyltrimethylammonium bromide in the pH range 10—14 but the pH dependence can be quite different from the 

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