Metal hydride reactions with

Using different reagents or under various conditions, 2,3-epoxy alcohols can undergo ring-opening reactions with metallic hydrides, giving 1,3-diols or 1,2-diols. As shown in Scheme 4-16, reduction of 3-substituted 2,3-epoxy alcohols with Red-Al leads to the exclusive formation of 1,3-diols, and this can be applied in the preparation of 1,3-diol compounds.31... 

Free Radical Reactions with Metal Hydrides... 

FREE RADICAL REACTIONS WITH METAL HYDRIDES... 

W(C0)3(CH3)(C5H5) reaction with metal hydrides 9.2.5.6 C9H9CrN303 Cr(CO)3(CH3CN)3... 

Bridged species such as 76 are well documented in rhodium porphyrin chemistry.240-241 An acetylene bonded to one metal-centered radical is presumed to be trapped by addition of a second metal-centered radical. Lower bond dissociation energies of cobalt relative to rhodium would disfavor species such as 76 and facilitate the reaction with metal—hydride intermediates to form a trans product. 

Reaction with metal hydrides and organometallic compounds... 

Treatment of 35 with alcohols in the presence of KOH at 50°C produces ammonia and hydrazine in moderate yields. Ammonia is the major product with all alcohols studied except for 2-propanol in which hydrazine is predominant. The molybdenum analog 25 gives no ammonia or hydrazine under these conditions. Hidai et al. have also carried out similar reactions with metal hydrides. Hydridic hydrides such as [(i7 -C5H5)2ZrHCl] and... 

Garbon-fluorine bonds of fluoroalkenes can be cleaved by reaction with metal hydrides to give HF and vinyl complexes. Thus, the rhodium compound [Rh (Z)-GF=GF(GF3) (PEt3)3] can be synthesized by regioselective G-F bond activation of hexafluoropropene at [RhH(PEt3)3] in the presence of Et3N/Gs2G03 (Scheme 10 left). ... 

FIGURE 16.65 Alcohols can be oxidized to carbonyl compounds. This reaction is the reverse of what you have just learned— the reduction of carbonyl compounds to alcohols through reactions with metal hydride reagents. 

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