Rapid microbiology continued

A rapid semiautomated microdilution method for the microbiological assay of the chloroquine has been developed by Desgardins (26). Antimalarial activity of chloroquine may be studied against cultured Plasmodium falciparum, microplates are used to prepare serial dilution of the drug. Parasites obtained from continuous stock cultures are subcultured in the micro-plates for 42 h. Inhibition of uptake of a radio labeled nucleic acid precursor by parasites serves as the indicator of antimicrobial activity. 

Aaron R.T., Davis R.C., Hamdy M.K. and Toledo R.T. Continuous alcohol/malolactic fermentation of grape must in a bioreactor system using immobilized cells. Journal of Rapid Methods and Automation in Microbiology 12 (2) (2004) 127-148. 

Research into new analytical techniques for foodstuffs continues, striving for greater accuracy, sensitivity or simplicity, for more rapid methods, for simultaneous multielement analysis, etc. Chromatographic techniques, e.g., LC, GLC, GC-MS, have led to great improvements in the levels of accuracy, sensitivity, and detection that can be achieved for many analytes including carbohydrates, certain vitamins, chemical residues, and additives. Work is still required, for instance, in the area of vitamin analysis in order to provide standard techniques that are applicable to all food types and that would enable concurrent multi-vitamin analysis to take place. Many of the microbiological assays currently used for vitamin determination involve long incubation times and more rapid techniques are needed. 

In the real world corrosion rates always change with time, for instance some forms of localized corrosion such as microbiologically influenced corrosion can accelerate rapidly and grow exponentially once initiated, and therefore it is important to identify the specific time periods of maximum corrosion rates and the effects of corrosion inhibitors. For this reason instantaneous techniques are important for continuous measirrement of the prevailing corrosion rates for... 

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