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Radiotherapy radio-chemotherapy

Local tumor recurrence with infiltration of the bladder or rectum but without extension to the pelvic sidewall can be treated by pelvic exenteration with curative intention. With strict patient selection, the 5-year-survival rate is 82% [63]. Various other surgical options are available for removal of recurrent tumor. In patients not having undergone radiotherapy or chemotherapy before, these therapeutic options are available for treating central pelvic recurrence. Repeat radiotherapy achieves successful local control with improvement of symptoms in cases of recurrent tumor outside the primary radiation field. Palliative chemotherapy is the final option available to all patients in whom curative surgery or radio(chemo)therapy is no longer possible. [Pg.128]

External radiotherapy provides sustained palliation in around 50% of patients. However, fibrotic strictures occur in 30% (Earlam and Cunha-Melo 1980). Chemotherapy has improved considerably in the last decade and now plays a useful role in palliation in some patients with advanced disease, resulting in some prolongation of life in 45% of patients (Webb et al. 1997), although the individual response to treatment remains unpredictable. The results of combined radio- and chemotherapy are better than either treatment alone, although toxicity is also increased. [Pg.22]


See other pages where Radiotherapy radio-chemotherapy is mentioned: [Pg.299]    [Pg.532]    [Pg.162]    [Pg.184]    [Pg.184]    [Pg.110]    [Pg.432]    [Pg.233]    [Pg.364]    [Pg.170]    [Pg.170]    [Pg.177]    [Pg.171]    [Pg.419]    [Pg.470]   
See also in sourсe #XX -- [ Pg.292 , Pg.299 ]




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