Radical concentrations Migration

In studies of peptides and proteins containing sulphydryl and disulphide groups irradiation at 77 K leads to non-S radicals, but on warming migration of spins to sulphur occurs and the stable radicals at higher temperature are thiyl radicals - . Other forms of energy transfer must also occur as the concentration of thiyl radicals eventually formed is higher than the total radical concentration at 77 K. 

Let us consider the case in which monomer is strongly bound to template. Initiation proceeds in a different way below and above the critical concentration of the template used. If concentration of the template is small and coils of the template are separated, primary radicals appear mainly outside the coils and then migrate to the sur-... 

Piroxicam, an oxicam (Figure 36-1), is a nonselective COX inhibitor that at high concentrations also inhibits polymorphonuclear leukocyte migration, decreases oxygen radical production, and inhibits lymphocyte function. Its long half-life (Table 36-1) permits once-daily dosing. 

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