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Radiation-associated malignancy

Radiation injury causes two types of effects on biologic symptoms, stochastic and deterministic. Stochastic effects are aU or nothing effects. At increasing doses, the probability of a stochastic effect increases, but once the stochastic effect occurs, further inaeases in exposure will not worsen the severity of the effect. A conunon stochastic effect is radiation-associated malignancy. In comparison, the severity of deterministic effects is proportional to the dose. Examples of deterministic effects include suppression of hematopoiesis, cataract formation and fertility impairment (4). [Pg.165]

ALL is associated with infiltration of the CNS and testes (Sanctuary sites). Prophylactic radiation and/or chemotherapy to the head is recommended because malignant cells in brain are protected from chemotherapy by the blood-brain barrier. [Pg.198]

See other pages where Radiation-associated malignancy is mentioned: [Pg.1305]    [Pg.2334]    [Pg.731]    [Pg.9]    [Pg.1292]    [Pg.1299]    [Pg.1382]    [Pg.1412]    [Pg.456]    [Pg.1727]    [Pg.135]    [Pg.141]    [Pg.14]    [Pg.76]    [Pg.129]    [Pg.139]    [Pg.140]    [Pg.362]    [Pg.461]    [Pg.173]    [Pg.547]    [Pg.1773]    [Pg.1165]    [Pg.60]    [Pg.119]    [Pg.181]    [Pg.123]    [Pg.404]    [Pg.192]    [Pg.259]    [Pg.403]    [Pg.3402]    [Pg.3570]    [Pg.179]    [Pg.192]    [Pg.193]    [Pg.206]    [Pg.2321]    [Pg.2324]    [Pg.2447]    [Pg.2448]    [Pg.2513]    [Pg.2544]    [Pg.385]    [Pg.239]    [Pg.195]    [Pg.74]    [Pg.148]   
See also in sourсe #XX -- [ Pg.165 ]



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