Quinocarcin antitumor activity

Katoh, T., Kirihara, M., Yoshino, T., Tamura, O., Ikeuchi, F., Nakatani, K., Matsuda, F., Yamada, K., Gomi, K., Ashizawa, T., Terashima, S. Synthetic studies on quinocarcin and its related compounds. 5. Synthesis and antitumor activity of various structural types of quinocarcin congeners. Tetrahedron 1994, 50, 6259-6270. 

The oxazolopyridine ring system is found embedded in the structures of a number of complex biologically active molecules such as the antibiotic streptazolin or the antitumor agent quinocarcin. Derivatives of the simple systems have not shown much by way of useful activity although some... 

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