Quasi-albumins

It must be pointed out that the so-called quasi-albumins described by Poulik and Smithies (P13) are immunologically unrelated to albumin and would be more appropriately named quasi-oi-globulins. These proteins migrate just behind albumin in the vertical starch-gel electrophoretic technique of Smithies (S34) and include the group-specific (Gc) components. A fetal plasma protein of similar electrophoretic mobility is known (B12, B13), whose carbohydrate content is 23 mg/g, which clearly distinguishes it from the glycoprotein fetuin. Occasionally the protein persists and can be observed in some neonatal blood plasmas. 

The flux of 3H-labeled PNU-78,517 across MDCK cell monolayers shows the characteristic disparity between the kinetics of disappearance from the donor solution and appearance in the receiver sink (Fig. 32). Drug uptake is rapid and exponential with time and approaches a quasi-equilibrium state in contrast, the concomitant efflux of drug into the receiver is slow and linear. While maintaining a 3% bovine serum albumin (BSA) concentration in the donor and varying the BSA concentration between 0.5 and 5% in the receiver, the results show that the... 

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